Skin tanning is a melanogenesis response to ultraviolet radiation DNA damage
the verdict
SUPPORTED
the evidence backs this
confidence 75/100
Extensive scientific evidence confirms that skin tanning (melanogenesis) functions as a protective response triggered by ultraviolet radiation-induced DNA damage and its subsequent repair.
Evidence for · 5
Skin pigmentation and its control: From ultraviolet radiation to stem cells.
2021 · cited by 0
Ultraviolet radiation causes keratinocyte DNA damage, triggering p53-mediated POMC expression and subsequent melanogenesis.
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More for · 4
DNA damage enhances melanogenesis.
1996 · cited by 0
DNA-damaging chemicals and ultraviolet irradiation upregulate tyrosinase and stimulate melanin production.
Melanogenesis: a photoprotective response to DNA damage?
2005 · cited by 0
Ultraviolet-induced DNA photodamage and its repair act as signals that stimulate melanogenesis.
Mechanisms of ultraviolet light-induced pigmentation.
1996 · cited by 0
Ultraviolet-induced melanogenesis functions as part of a protective response to damaging ultraviolet irradiation.
DNA photodamage stimulates melanogenesis and other photoprotective responses.
1999 · cited by 0
DNA damage or DNA repair intermediates directly trigger tanning and other photoprotective responses.