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the claim
RISUG provides a simple and effective form of male birth control
the verdict
SUPPORTED
the evidence backs this
confidence 78/100

Clinical and experimental studies indicate that RISUG is a safe, effective, and potentially reversible form of non-hormonal male contraception.

Evidence for · 8
Studies on biochemical, oxidative and genotoxicity alterations following vas blockage with reversible inhibition of sperm under guidance and reversal in rats
2022 · cited by 2
Demonstrates that RISUG vas occlusion and its reversal procedures in rats do not cause significant toxicological manifestations or oxidative stress.
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More for · 7
Reversible inhibition of sperm under guidance as an intratubular and reversible contraception in female rats: An experimental study
2021 · cited by 0
Shows that RISUG provides effective and reversible tubular occlusion in animal experimental models.
RISUG: an intravasal injectable male contraceptive.
2014 · cited by 0
Highlights RISUG as a promising long-term, single-injection male contraceptive with demonstrated reversibility.
A short-term evaluation of semen and accessory sex gland function in phase III trial subjects receiving intravasal contraceptive RISUG.
2003 · cited by 0
Confirms that RISUG effectively acts as an occluding agent in the vas deferens, successfully preventing pregnancy in human subjects.
Safety & efficacy of an intravasal, one-time injectable & non-hormonal male contraceptive (RISUG): A clinical experience.
2019 · cited by 0
Clinical trial data in human volunteers shows that RISUG is a safe procedure with high sustained contraceptive efficacy and minimal adverse effects.
Can the evolution of male contraception lead to a revolution? Review of the current state of knowledge.
2018 · cited by 0
Evaluates non-hormonal male contraceptives and recognizes RISUG as a very promising option close to market introduction.
RISUG® as a male contraceptive: journey from bench to bedside.
2020 · cited by 0
Reviews the developmental journey of RISUG as a safe, effective, and long-term male contraceptive alternative to vasectomy.
Relative suitability of DMSO and NaHCO3 for reversal of RISUG® induced long-term contraception.
2016 · cited by 0
Demonstrates that RISUG induces long-term contraception that can be successfully reversed using DMSO or NaHCO3.
The paper trail · every fact has a biography
first checked01 Aug 2026
judged → SUPPORTED · 7801 Aug 2026
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