Resting potentials and action potential thresholds are uniform across all neurons in a network
the verdict
REFUTED
the evidence says no
confidence 3/100
Resting membrane potentials and action potential thresholds are not uniform across neurons; rather, they vary widely depending on cell type, brain region, morphology, and physiological state.
Evidence against · 3
Input-Specific Organization of Intrinsic Excitability Expands Coding Capacity of Fast-Spiking Auditory Neurons.
2025 · cited by 2
Demonstrates that neurons within the same population (MNTB principal neurons) display distinct input resistances and resting potassium conductances, resulting in heterogeneous firing properties.
See more details
More against · 2
Decreases in the sustained firing capacity of layer 2/3 pyramidal neurons in the anterior cingulate cortex of aged rats.
2026 · cited by 0
Shows that neuronal aging alters intrinsic membrane properties, leading to depolarized resting membrane potentials and shifted action potential thresholds.
Effects of Apical Dendrite Integrity on Action Potential Properties in Layer 6 Corticothalamic Pyramidal Neurons: Evidence for Hemispheric Differences.
2026 · cited by 0
Finds that even within the same neuronal subtype (layer 6 corticothalamic pyramidal neurons), action potential thresholds and properties differ significantly depending on hemisphere and dendritic integrity.