Rapidly-progressing myopia is caused by specific environmental and genetic factors
Current medical literature consistently supports the consensus that both environmental and genetic factors contribute to the pathogenesis and progression of myopia.
The retrieved literature consistently notes that myopia development and progression are multifactorial conditions influenced by both genetic predisposition and environmental factors. Papers 1, 4, and 6 explicitly state or review the interplay of genetic and environmental risk factors in myopia pathogenesis. None of the papers refute this claim.
Han X, Liu C, Chen Y, He M. Myopia prediction: a systematic review.. 2022. https://doi.org/10.1038/s41433-021-01805-6
Reviews how genetic data, lifestyle data, and other factors help predict myopia risk and progression.
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Vishweswaraiah S, Swierkowska J, Ratnamala U, Mishra NK, Guda C, Chettiar SS, Johar KR, Mrugacz M, Karolak JA, Gajecka M, Radhakrishna U. Epigenetically dysregulated genes and pathways implicated in the pathogenesis of non-syndromic high myopia.. 2019. https://doi.org/10.1038/s41598-019-40299-x
Discusses how both genetic and environmental factors play a key role in the development and pathophysiology of myopia.
Zhang D, Wang L, Jin L, Wen Y, Zhang X, Zhang L, Zhu H, Wang Z, Yu X, Xie C, Tong J, Shen Y. A Review of Intraocular Pressure (IOP) and Axial Myopia.. 2022. https://doi.org/10.1155/2022/5626479
Notes that the pathogenesis of myopia is driven by a combination of genetic and environmental risk factors.
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