Radial artery access for angiography has fewer complications than femoral artery access
Extensive clinical literature and guideline recommendations consistently support the conclusion that radial artery access for angiography and interventions has fewer vascular complications, particularly bleeding and access-site trauma, compared to femoral artery access.
The retrieved literature strongly and consistently supports the claim that transradial access has fewer complications (such as bleeding and vascular events) compared to transfemoral access. Multiple reviews and clinical studies confirm that transradial access is the preferred default approach in modern interventional cardiology due to its superior safety profile.
Nasser A, Malkowski A, Żądło A, Michalczak M, Dziewierz A, Tokarek T. Radial artery access in interventional cardiology: a review of current practices.. 2025. https://doi.org/10.5114/aic.2025.158053
This review notes that transradial access is the guideline-recommended default strategy due to its association with improved clinical outcomes, fewer complications, and enhanced patient comfort compared with transfemoral access.
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Attachaipanich T, Khawaja M, Takahashi EA, Virk HUH, Alam M, Gilchrist IC, Krittanawong C. Percutaneous Coronary Intervention and vascular access complications: A contemporary review.. 2026. https://doi.org/10.1038/s44325-026-00125-6
This contemporary review states that the transradial approach is preferred over the transfemoral approach for percutaneous coronary interventions due to lower bleeding, vascular complications, and mortality.
Kulkarni AV, Bahiru A, Manjunath D, Murali MJ, Khaleel H. Initial arterial access used and associated factors in coronary procedures: A retrospective study from a tertiary indian center.. 2026. https://doi.org/10.1371/journal.pone.0344998
This retrospective study indicates that transradial access was associated with fewer complications during coronary procedures compared to transfemoral access.
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