Protein structure can be determined by X-ray diffraction using a single diffraction image
the verdict
SUPPORTED
the evidence backs this
confidence 75/100
Protein structures can theoretically be determined from single-molecule diffraction images using intense X-ray pulses and oversampling methods to solve the phase problem.
Evidence for · 2
Taking X-ray diffraction to the limit: macromolecular structures from femtosecond X-ray pulses and diffraction microscopy of cells with synchrotron radiation.
2004 · cited by 0
Discusses how continuous diffraction patterns from single noncrystalline specimens can solve the phase problem using the oversampling method.
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More for · 1
An approach to three-dimensional structures of biomolecules by using single-molecule diffraction images.
2001 · cited by 0
Demonstrates that 3D structural determination of macromolecules can be achieved by combining ultrashort x-ray pulses for single-molecule diffraction with direct phase retrieval.