Probiotics exist that specifically target upper respiratory tract tissue
the verdict
SUPPORTED
the evidence backs this
confidence 84/100
Clinical and review evidence demonstrates that specific probiotic strains, such as Streptococcus salivarius administered via nasal spray or lozenge, are designed and shown to target upper respiratory tract tissue to prevent and reduce infections.
Evidence for · 6
Bacteriotherapy with Streptococcus salivarius 24SMB and Streptococcus oralis 89a nasal spray for treatment of upper respiratory tract infections in children: a pilot study on short-term efficacy
2020 · cited by 27
Demonstrates the use of Streptococcus salivarius nasal sprays specifically to treat upper respiratory tract issues.
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More for · 5
Streptococcus salivarius Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review
2024 · cited by 14
Reviews the prophylactic use of S. salivarius strains like 24SMB via intranasal administration to target respiratory disease.
Efficacy of Streptococcus salivarius Blis K12 in the Prevention of Upper Respiratory Tract Infections in Physically Active Individuals: A Randomized Controlled Trial
2024 · cited by 9
Shows that Streptococcus salivarius K12 successfully prevents upper respiratory tract infections in clinical trials.
Review of Streptococcus salivarius BLIS K12 in the Prevention and Modulation of Viral Infections
2025 · cited by 5
Highlights how bacteriocin-producing probiotics specifically target infections within the upper respiratory tract.
The response of nasal epithelial cells exposed to novel Lactobacillus and alpha-haemolytic Streptococcus isolated from the upper respiratory tract of children.
2025 · cited by 1
Examines the direct response of nasal epithelial cells to novel and commercial probiotic strains targeted for the respiratory tract.
Streptococcus salivarius K12: A comprehensive review on its role as a probiotic in pediatric and general health
2025 · cited by 0
Discusses the role of S. salivarius K12 as a targeted probiotic for enhancing upper respiratory tract health.