Prefrontal cortex development varies significantly across individuals
the verdict
SUPPORTED
the evidence backs this
confidence 77/100
Multiple neuroimaging and molecular studies demonstrate that prefrontal cortex development exhibits substantial individual variability in structural connectivity, molecular signatures, and functional activation trajectories across adolescence and maturation.
Evidence for · 4
Hierarchical maturation of structural brain connectomes from birth to childhood.
2026 · cited by 1
Paper 0 establishes that structural connectome development features prolonged modular reconfiguration and hub consolidation involving the prefrontal cortex across individuals.
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More for · 3
Developmental trajectories of prefrontal activation underlying emotional inhibitory control from adolescence to young adulthood: a functional near-infrared spectroscopy study.
2026 · cited by 0
Paper 7 demonstrates age-related differences in prefrontal activation and lateralization during cognitive control tasks from adolescence to young adulthood.
Intrinsic coordination of dynamic molecular signatures shape the human prefrontal cortex
2026 · cited by 0
Paper 9 highlights specialized molecular signatures and intrinsic determinants that orchestrate human prefrontal cortex development and identity.
Transdiagnostic divergent neural development of reward anticipation in early adolescents at risk for depression and psychosis.
2026 · cited by 0
Paper 11 shows divergent developmental trajectories of prefrontal-limbic activation and reward anticipation among adolescents.