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the claim
Prediabetes causes coronary heart disease
the verdict
SUPPORTED
the evidence backs this
confidence 82/100

Current clinical evidence and Mendelian randomization studies support the conclusion that prediabetes is an independent risk factor causally associated with an increased incidence of coronary heart disease.

Evidence for · 2
Correlation between prediabetes and coronary artery disease severity in patients undergoing elective coronary angiography
2019 · cited by 10
Paper [2] demonstrates that prediabetes is associated with a high atherosclerotic burden and coronary artery disease complexity comparable to diabetes.
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More for · 1
Prognostic stratification of cardiovascular risk and cardiac remodeling in prediabetes: a multimodal analysis comparing ADA and WHO/IEC diagnostic criteria.
2026 · cited by 0
Paper [9] confirms via Mendelian randomization and large-scale prospective analysis that prediabetes is causally associated with increased risks of coronary heart disease and cardiovascular disease.
The paper trail · every fact has a biography
first checked02 Aug 2026
judged → SUPPORTED · 8202 Aug 2026
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