Pesticide exposure significantly increases the risk of developing Parkinson's disease
the verdict
SUPPORTED
the evidence backs this
confidence 79/100
Multiple epidemiological reviews, experimental studies, and toxicological overviews consistently support the conclusion that pesticide exposure significantly increases the risk of developing Parkinson's disease.
Evidence for · 6
Pesticide exposure and the development of Parkinson disease: a systematic review of Brazilian studies.
2025 · cited by 3
A systematic review of Brazilian studies indicates an association between pesticide exposure and an increased occurrence of Parkinson's disease.
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More for · 5
Pesticides and parkinson's disease: causal relationship at the population and individual level?
2026 · cited by 1
A review on pesticides and Parkinson's disease highlights that pesticide exposure is associated with an increased risk of the disease, leading to occupational recognition in France and Germany.
Preventing Parkinson's disease in the context of movement disorders: a narrative review of current evidence and future directions.
2026 · cited by 1
A narrative review on preventing Parkinson's disease identifies pesticide exposure as a well-supported relevant risk factor.
Genome-wide analysis reveals genes mediating resistance to paraquat neurodegeneration in Drosophila.
2025 · cited by 1
A genome-wide analysis in Drosophila supports the mechanistic role of gene-environment interactions in pesticide-related neurodegeneration linked to Parkinson's risk.
Insulin resistance induced by pesticides is overcome by pancreatic islet adaptation in a mouse model of Parkinson's disease.
2026 · cited by 0
A mouse model study demonstrates that chronic dietary exposure to pesticides leads to motor deficits and metabolic alterations associated with Parkinson's disease.
Environmental Substances Associated with Neurodegeneration: An Overview of Parkinson's Disease and Related Genotoxic Endpoints.
2026 · cited by 0
An overview of environmental substances associated with neurodegeneration highlights pesticides as agents with direct or probable association with Parkinson's disease risk.