Oral sex carries a significant risk of transmitting genital HSV-1
Oral sex is a well-documented transmission route for herpes simplex virus type 1 (HSV-1) to the genital tract, with studies showing that HSV-1 now accounts for a substantial proportion of new genital herpes cases globally.
The retrieved papers consistently demonstrate that HSV-1 is frequently transmitted to the genital region (often via oral-genital contact), contributing significantly to the global burden of genital herpes. Therefore, the claim is supported by the literature.
M. Harfouche, S. AlMukdad, Asalah Alareeki, Aisha M M Osman, Sami L. Gottlieb, Jane Rowley, L. Abu-Raddad, K. Looker. Estimated global and regional incidence and prevalence of herpes simplex virus infections and genital ulcer disease in 2020: mathematical modelling analyses. 2024. https://doi.org/10.1136/sextrans-2024-056307
Mathematical modeling analyses show millions of new genital HSV-1 infections occurring globally, highlighting substantial transmission.
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R. Ageeb, M. Harfouche, H. Chemaitelly, L. Abu-Raddad. Epidemiology of herpes simplex virus type 1 in the United States: Systematic review, meta-analyses, and meta-regressions. 2024. https://doi.org/10.1016/j.isci.2024.110652
Systematic reviews document that genital acquisition of HSV-1 has increased significantly over time.
Collins-Ogle M, Herold BC. Developments in genital herpes: progress in prevention and treatment.. 2026. https://doi.org/10.1097/qco.0000000000001177
Recent literature notes that HSV-1 now accounts for a large proportion of new genital herpes infections globally, largely driven by changing sexual practices such as oral sex.
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