popularly believed that one human year equals seven dog years. This is inaccurate since dogs are able to reproduce from the age of 1. One size fits all — A Aging in dogs varies from breed to breed, and affects the dog's health and physical ability. As with humans, advanced years often bring changes in a dog's ability to hear, see, and move about easily. Skin condition, appetite, and energy levels often degrade with geriatric age. Medical conditions such as cancer, kidney failure, arthritis, dementia, and joint conditions, and other signs of old age m O… Popular myth — It is popularly believed that one human year equals seven dog years. This is inaccurate since dogs are able to reproduce from the age of 1. One size fits all — A rule of thumb is that the first year of a dog's life is equivalent to 15 human years, the second year equivalent to 9 human years, and each subsequent year about 5 human years. So, a dog age 2 is equivalent to a human age 24, while a dog age 10 is equivalent to a human age 64. This is more accurate but still fails to account for size/breed, which is a significant factor. Size- or breed-specific calculators — These try to factor in the size or breed as well. These are the most accurate types. They typically work either by expected adult weight or by categorizing the dog as "small", "medium", or "large". No one formula for dog-to-human age conversion is scientifically agreed on, although within fairly close limits they show great similarities. Researchers suggest that dog age depends on DNA methylation which is an epigenetic process. Epigenetic changes occur nonlinear in dogs compared to human. Oxidative stress appears to be a significant determinant of longevity in small breed compared to large breed dogs. Oxidative damage to DNA can be measured by assessing the level of 8-Oxo-2'-deoxyguanosine in DNA. Oxidative DNA damage measured in puppies was found to be higher in larger dog breeds with shorter lifespans than in smaller breed dogs with longer life spans. This result suggested that DNA repair mechanisms fail earlier in larger breed dogs so that more DNA damage is accumulated sooner in these breeds leading to reduced longevity. Emotional maturity occurs, as with humans, over an extended period of time and in stages. As in other areas, development of giant breeds is slightly delayed compared to other breeds, and, as with humans, there is a difference between adulthood and full maturity (compare humans age 20 and age 40 for example). In all but large breeds, sociosexual interest arises around 6–9 months, becoming emotionally adult around 15–18 months and fully mature around 3–4 years, although as with humans learning and refinement continue thereafter. According to the UC Davis Book of…