Throughout the history of human spaceflight, spacefarers have experienced and reported the occurrence of medical conditions, including various illnesses and injuries. Therefore, future spaceflight missions to the Moon and Mars will require the capabilities necessary for maintaining the health of these new space travelers. Mass, power, and volume available in the space vehicles used for these missions will be severely constrained. The ability to resupply or evacuate to Earth will be limited or non-existent, and ground-based support will no longer be immediate due to communication latencies and blackouts. These vehicle and mission constraints will necessitate healthcare be provided from an efficiently planned medical system. To provide the necessary care, these medical systems will need to include at a minimum, several different types of medical devices, consumable resources, centralized data management, procedural guidance, and decision support technologies. Medical devices needed for diagnosing and treating medical conditions that are expected to occur during future spaceflight missions may include real-time health monitoring, medical imaging capabilities, as well as blood and urine analysis. Novel methods for interacting with onboard patient medical records will be necessary, as will resource tracking. Terrestrial medicine shares many of these same needs, therefore a multitude of these required medical capabilities can likely be satisfied by currently available, Commercial-Off-The-Shelf (COTS) devices and methodologies; however, in some cases the unique space environment and increased mission durations will drive the need for modifications or customization of standard technologies and treatment procedures. This article will provide a review of medical devices and technologies that have been considered for inclusion within future spaceflight medical systems. It will also include a discussion about the modifications and customized development that have been performed, as well as descriptions of the technology demonstrations that have been conducted in analog and spaceflight environments.

Human space missions beyond Low Earth Orbit (LEO), such as to the Moon and Mars, will require increased crew autonomy in health management, due to communication delays and limited resupply. These missions pose unique biomedical challenges, including radiation exposure, altered gravity, and prolonged isolation, which can affect physiology and compromise available treatments. This review examines current efforts in pharmaceutical and biomedical strategies to support health preservation during long-duration missions. We discuss technologies needed to assure drug stability and storage, also considering potential modifications of pharmacokinetics in space, and the potential of nanotechnologies, physical therapies, and in-situ manufacturing. Non-pharmacological tools for diagnostics, trauma care, and tissue regeneration are highlighted for their promise in enhancing medical self-sufficiency. These advances are not only critical for ensuring mission success and crew safety beyond LEO, yet may also translate to healthcare solutions in remote or underserved Earth settings.

The National Aeronautics and Space Administration (NASA ) is an independent agency of the U.S. federal government responsible for the United States' civil space program, as well as research in aeronautics and space. Headquartered in Washington, D.C., NASA operates ten field centers across the US and is organized into three mission directorates: Human Spaceflight, Research and Technology, and Scien NASA's Human Research Program (HRP) is designed to study the effects of space on human health and also to provide countermeasures and technologies for human space exploration. The medical effects of space exploration are reasonably limited in low Earth orbit or in travel to the Moon. Travel to Mars is significantly longer and deeper into space, significant medical issues can result. These include bone density loss, radiation exposure, vision changes, circadian rhythm disturbances, heart remodeling, and immune alterations. In order to study and diagnose these ill-effects, HRP has been tasked with identifying or developing small portable instrumentation with low mass, volume, and power to monitor the health of astronauts. As part of the effort to achieve this aim, on May 13, 2022, NASA and SpaceX Crew-4 astronauts successfully tested the rHEALTH ONE, a miniature cytometry-based biomedical analyzer, for its ability to identify and analyze biomarkers, cells, microorganisms, and proteins in a spaceflight environment. Educational Launch of Nanosatellites (ELaNa). Since 2011, the ELaNa program has provided opportunities for NASA to work with university teams to test emerging technologies and commercial-off-the-shelf solutions by providing launch opportunities for developed CubeSats using NASA procured launch opportunities. By example, two NASA-sponsored CubeSats launched in June 2022 on a Virgin Orbit LauncherOne vehicle as the ELaNa 39 mission. Cubes in Space. NASA started an annual competition in 2014 named "Cubes in Space". It is jointly organized by NASA and the global education company I Doodle Learning, with the objective of teaching school students aged 11–18 to design and build scientific experiments to be launched into space on a NASA rocket or balloon. On June 21, 2017, the world's smallest satellite, KalamSAT, was launched.

Space Flight (HSF) website The Apollo Program at the NASA History Program Office "Apollo Spinoffs". Archived from the original on April 4, 2012. The Apollo The Apollo program, also known as Project Apollo, was the United States human spaceflight program led by NASA, which landed the first humans on the Moon in 1969. Apollo was conceived in 1960 in the Dwight D. Eisenhower presidency during Project Mercury and executed after Project Gemini. Apollo was later dedicated to President John F. Kennedy's national goal, "before this decade is out, of landing The Apollo program has been described as the greatest technological achievement in human history. Apollo stimulated many areas of technology, leading to over 1,800 spinoff products as of 2015, including advances in the development of cordless power tools, fireproof materials, heart monitors, solar panels, digital imaging, and the use of…