Nucleated red blood cells in reptiles, birds, and fish serve specific physiological functions
the verdict
SUPPORTED
the evidence backs this
confidence 88/100
Evidence from multiple studies confirms that nucleated red blood cells in non-mammalian vertebrates like fish and birds participate in active physiological processes, such as immune responses and enzymatic regulation.
Evidence for · 3
Blood Will Tell: What Hematological Analyses Can Reveal About Fish Welfare.
2021 · cited by 96
Paper 0 notes that fish blood composition, including the nucleation of distinct cells, requires careful evaluation in physiological and welfare assessments.
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More for · 2
Transcriptomic analysis of immune response to bacterial lipopolysaccharide in zebra finch (Taeniopygia guttata).
2019 · cited by 18
Paper 4 demonstrates that unlike mammals, birds have nucleated red blood cells that exhibit a distinct transcriptomic response to immune challenges.
On the history of ecto-ATPases: The role of W. A. Engelhardt
2007 · cited by 3
Paper 10 discusses the historical discovery of specialized surface enzymes like ecto-ATPase on nucleated avian, amphibian, and fish erythrocytes.