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the claim

Nicotine worsens Crohn's disease symptoms

the verdict

SUPPORTED

the evidence backs this

confidence 88/100

Evidence consistently indicates that tobacco smoking and nicotine delivery systems negatively impact clinical outcomes and disease progression in Crohn's disease.

Evidence for · 2

Epidemiology of Inflammatory Bowel Disease across the Ages in the Era of Advanced Therapies.

2024 · cited by 96

The review notes that smoking has consistently been shown to negatively impact disease outcomes for Crohn's disease.

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More for · 1

Electronic Nicotine Delivery Systems and Clinical Outcomes in Adults With Inflammatory Bowel Disease: A Systematic Review of Emerging Evidence.

2026 · cited by 0

The systematic review indicates that e-cigarette use is associated with a signal for higher postoperative endoscopic recurrence in Crohn's disease.

The paper trail · every fact has a biography

first checked02 Aug 2026

judged → SUPPORTED · 8802 Aug 2026

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