Neuroplasticity decreases in adults due to specific biological maturation processes
the verdict
SUPPORTED
the evidence backs this
confidence 77/100
Biological maturation processes, such as the development of inhibitory circuits and extracellular matrix changes, progressively constrain neuroplasticity as individuals age.
Evidence for · 3
Comparative Neuroplasticity in Frontal- and Lateral-Eyed Mammals With Induced-Binocular Vision Dysfunction: Insights From Monocular Deprivation Models.
2025 · cited by 1
Paper 3 notes that visual cortical plasticity is fine-tuned and constrained through extended critical periods and maturation processes.
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More for · 2
Early life shifts in cortical inhibitory-excitatory balance underlies sensitive periods and skill development.
2026 · cited by 0
Paper 5 discusses how the maturation of GABAergic interneurons and shifts in excitation-inhibition balance gate and close critical periods of plasticity.
Tuning excitatory input to fast-spiking parvalbumin-positive interneurons: a lever for plasticity and hyperexcitability across the lifespan.
2026 · cited by 0
Paper 9 explains that neuroplasticity is high during early critical periods and increasingly constrained with biological maturation and aging.