Neurons and glial cells undergo migration during development and neurogenesis
Extensive scientific evidence confirms that both neurons and glial cells undergo active migration and engage in guided interactions during neurogenesis and brain development.
The claim is specific, empirical, and well-supported by multiple developmental neurobiology studies showing that neurons migrate along glial fibers and that glial cells themselves migrate and position during embryonic and postnatal development.
UE Gasser, ME Hatten. Neuron-glia interactions of rat hippocampal cells in vitro: glial- guided neuronal migration and neuronal regulation of glial differentiation. 1990. https://doi.org/10.1523/jneurosci.10-04-01276.1990
Paper 0 demonstrates that hippocampal astroglial cells support extensive glial-guided neuronal migration during development.
See more details
M E Hatten. Central nervous system neuronal migration.. 1999. https://doi.org/10.1146/annurev.neuro.22.1.511
Paper 5 reviews how postmitotic neurons undergo directed migrations along glial fiber systems during vertebrate brain development.
Jonathan I Lake, Robert O Heuckeroth. Enteric nervous system development: migration, differentiation, and disease.. 2013. https://doi.org/10.1152/ajpgi.00452.2012
Paper 7 notes that enteric nervous system development involves neural crest-derived cells migrating and differentiating into glia and neurons.
Zhihao Zhou, Penghui Wang, Qing Wang, Zhangji Dong, Xu Chen, Run Zhuo, Ronghua Wu, Yan Liu, Liu Yang, Mei Liu. SASH1 contributes to glial cell migration in the early development of the central nervous system.. 2023. https://doi.org/10.1016/j.ydbio.2023.09.006
Paper 11 reports that SASH1 plays an important role in regulating the migration and arrangement of glial cells during embryonic brain development.
The paper trail · every fact has a biography
Challenge the receipt
Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.
Terms · Privacy · How verdicts work · Dispute this receipt