Modern medicine has halted human biological evolution
the verdict
REFUTED
the evidence says no
refutedsupported
the weight of evidence
0 sources for · 2 against
Reference sources and scientific literature indicate that humans are still actively evolving and that selective sweeps continue in modern human populations, directly contradicting the claim that human biological evolution has halted.
Recent studies have made great strides towards identifying putative genetic events underlying the evolution of the human brain and its emergent cognitive capacities. One of the most intriguing findings is the recurrent identification of adaptive evolution in genes associated with primary microcephaly, a developmental disorder characterized by severe reduction in brain size and intelligence, reminiscent of the early hominid condition. This has led to the hypothesis that the adaptive evolution of these genes has contributed to the emergence of modern human cognition. As with other candidate loci, however, this hypothesis remains speculative due to the current lack of methodologies for characterizing the evolutionary function of these genes in humans. Two primary microcephaly genes, ASPM and Microcephalin, have been implicated not only in the adaptive evolution of the lineage leading to humans, but in ongoing selective sweeps in modern humans as well. The presence of both the putatively adaptive and neutral alleles at these loci provides a unique opportunity for using normal trait variation within humans to test the hypothesis that the recent selective sweeps are driven by an advantage in cognitive abilities. Here, we report a large-scale association study between the adaptive alleles of these genes and normal variation in several measures of IQ. Five independent samples were used, totaling 2393 subjects, including both family-based and population-based datasets. Our overall findings do not support a detectable association between the recent adaptive evolution of either ASPM or Microcephalin and changes in IQ. As we enter the post-genomic era, with the number of candidate loci underlying human evolution growing rapidly, our findings highlight the importance of direct experimental validation in elucidating their evolutionary role in shaping the human phenotype.
selective force in human evolution and has accelerated it; however, this is disputed. With a sufficiently large data set and modern research methods, scientists
Recent human evolution refers to evolutionary adaptation, sexual and natural selection, and genetic drift within Homo sapiens populations, since their separation and dispersal in the Middle Paleolithic about 50,000 years ago. Contrary to popular belief, not only are humans still evolving, their evolution since the dawn of agriculture is faster than ever before. It has been proposed that human cult
A 2017 study by researchers from Northwestern University unveiled a mutation among the Old Order Amish living in Berne, Indiana, that suppressed their chances of having diabetes and extends their life expectancy by about ten years on average. That mutation occurred in the gene called Serpine1, which codes for the production of the protein PAI-1 (plasminogen activator inhibitor), which regulates blood clotting and plays a role in the aging process. About 24% of the people sampled carried this mutation and had a life expectancy of 85, higher than the community average of 75. Researchers also found the telomeres—non-functional ends of human chromosomes—of those with the mutation to be longer than those without. Because telomeres shorten as the person ages, those with longer telomeres tend to live longer. At present, the Amish live in 22 U.S. states plus the Canadian province of Ontario. They live simple lifestyles that date back centuries and generally insulate themselves from modern North American society. They are mostly indifferent towards modern medicine, but scientists do have a healthy relationship with the Amish community in Berne. Their detailed genealogical records make them ideal subjects for research.
In 2020, Teghan Lucas, Maciej Henneberg, Jaliya Kumaratilake gave evidence that a growing share of the human population retained the median artery in their forearms. This structure forms during fetal development but dissolves once two other arteries, the radial and ulnar arteries, develop. The median artery allows for more blood flow and could be used as a replacement in certain surgeries. Their statistical analysis suggested that the retention of the median artery was under extremely strong selection within the last 250 years or so. People have been studying this structure and its prevalence since the eighteenth century.
Multidisciplinary research suggests that ongoing evolution could help explain the rise of certain medical conditions such as autism and autoimmune disorders. Autism and schizophrenia may be due to genes inherited from the mother and the father which are over-expressed and which fight a tug-of-war in the child's body. Allergies, asthma,…
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