Mitochondria are transferable between cell types, individuals, and species
the verdict
SUPPORTED
the evidence backs this
confidence 84/100
Mitochondria are increasingly recognized as mobile organelles capable of being naturally transferred between cells or artificially transplanted via extracellular vesicles, tunneling nanotubes, and cell-based therapies.
Evidence for · 9
Highly Specialized Mechanisms for Mitochondrial Transport in Neurons: From Intracellular Mobility to Intercellular Transfer of Mitochondria
2023 · cited by 22
Paper [0] reviews how motor proteins facilitate the intercellular transfer of mitochondria between cells.
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More for · 8
Mitochondrial transplantation: a promising strategy for treating degenerative joint diseases
2024 · cited by 16
Paper [1] discusses artificial mitochondrial transplantation and intercellular transfer as strategies for treating degenerative diseases.
Enhancing the therapeutic efficacy of mesenchymal stem cell transplantation in diabetes: Amelioration of mitochondrial dysfunction-induced senescence.
2023 · cited by 16
Paper [2] highlights intercellular mitochondrial transfer as a key mechanism in mesenchymal stem cell therapies.
A promising therapeutic: Exosome-mediated mitochondrial transplantation.
2024 · cited by 12
Paper [3] outlines extracellular vesicle-mediated mitochondrial transplantation across various systemic diseases.
Mitochondrial transfer in cancer: mechanisms, immune evasion, and therapeutic opportunities.
2026 · cited by 4
Paper [5] details how intact mitochondria are exchanged between tumor cells, stromal elements, and immune cells.
Mitochondrial Transplantation: A Paradigm Shift in Osteoporosis Therapy
2025 · cited by 2
Paper [6] describes mitochondrial transplantation involving the transfer of functional mitochondria to metabolically compromised cells.
Unlocking extracellular mitochondria from bench to clinical application in stroke.
2025 · cited by 1
Paper [8] explains that metabolically active mitochondria can be released into the extracellular space and taken up by other cells.
Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases.
2026 · cited by 1
Paper [9] examines the delivery of healthy exogenous mitochondria to target cells as a therapeutic strategy.
Mitochondrial Transfer: From Bench to Bedside.
2026 · cited by 1
Paper [10] recognizes mitochondria as mobile organelles that move between cells via tunneling nanotubes and extracellular vesicles.