Recent meta-analytic evidence indicates that males exhibit significantly higher pain thresholds and tolerances compared to females, with biological factors such as testosterone levels playing a contributing role.
Paper [2] provides direct, high-level meta-analytic evidence showing that males have significantly higher pain thresholds and tolerances than females. Paper [5] supports the biological plausibility of this difference by demonstrating that testosterone has an antinociceptive effect, correlating positively with pain tolerance in men. Papers [1] and [3] also identify female sex as a predictor of higher pain sensitivity or symptom severity in specific contexts. No papers in the provided set refute the claim.