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the claim

Mederma is effective for scar removal

the verdict
CONTESTED
contested - the weight sits with the refuting side
Recorded sources
2 sources for · 3 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

The efficacy of Mederma and its active ingredient, onion extract, for scar removal is contested, with clinical trials and reviews showing mixed results compared to standard silicone therapies and controls.

The analysis

While some preliminary or narrative reviews include onion extract among possible topical options and specific trials note minor improvements in metrics like erythema, rigorous comparative studies and other reviews find no significant superiority over petrolatum or control emollients, concluding that onion extract lacks robust evidence of efficacy compared to standard silicone-based treatments.

The evidence we hold leans leans refuted

How this was weighed

official record 3x · fact-check 2x · hedged 1x · crowd & reference 1x

  • Evaluating efficacy and safety of the topical silicone gel c · peer-reviewed · supports · weight 1.05 · 2021
  • Evidence-Based Topical Therapy for Facial Scars in Diverse S · peer-reviewed · supports · weight 1 · 2025
  • Comparison of the Effectiveness of Onion Extract, Topical St · peer-reviewed · refutes · weight 1.05 · 2020
  • Pediatric Facial Lacerations: Evidence-Based Over-the-Counte · peer-reviewed · refutes · weight 1 · 2025
  • Strategies to improve facial scars following Mohs micrograph · peer-reviewed · refutes · weight 1 · 2025
Evidence for · 2
Evaluating efficacy and safety of the topical silicone gel containing onion extract in the treatment of post‐cesarean surgical scars
Recorded source metadata

Supamas Napavichayanun, Apichai Vasuratna, Somsook Santibenchakul, Sarocha Cherdchom, Pornanong Aramwit. Evaluating efficacy and safety of the topical silicone gel containing onion extract in the treatment of post‐cesarean surgical scars. 2021. https://doi.org/10.1111/jocd.14524

This study suggests that silicone gel containing onion extract improves scar erythema compared to control.

Evidence against · 3
Comparison of the Effectiveness of Onion Extract, Topical Steroid, and Petrolatum Emollient in Cosmetic Appearance of Upper Blepharoplasty Scar
Recorded source metadata

Naser Owji, Mohammad Reza Khalili, Behzad Khademi, Mohammad Shirvani, Maryam Sadat Sadati. Comparison of the Effectiveness of Onion Extract, Topical Steroid, and Petrolatum Emollient in Cosmetic Appearance of Upper Blepharoplasty Scar. 2020. https://doi.org/10.4103/joco.joco_39_20

This trial found no significant differences in scar appearance between onion extract, topical steroids, and petrolatum emollient.

See more details
More for · 1
Evidence-Based Topical Therapy for Facial Scars in Diverse Skin Types.
Recorded source metadata

Kazemeini S, Nadeem-Tariq A, Luthra A, Suha R, Turna A, Easterly J, Pokharel S, Muqaddas S, Kazemeini M. Evidence-Based Topical Therapy for Facial Scars in Diverse Skin Types.. 2025. https://doi.org/10.7759/cureus.86343

This review lists onion extract among agents supported for scar modulation in a phase-specific approach.

More against · 2
Pediatric Facial Lacerations: Evidence-Based Over-the-Counter Wound Care and Scar Prevention for Clinicians and Caregivers.
Recorded source metadata

Antonious K. Pediatric Facial Lacerations: Evidence-Based Over-the-Counter Wound Care and Scar Prevention for Clinicians and Caregivers.. 2025. https://doi.org/10.7759/cureus.85909

This review notes that over-the-counter products like onion extract offer minimal benefit compared to silicone-based therapies.

Strategies to improve facial scars following Mohs micrographic surgery.
Recorded source metadata

Lim Y, Avram M, Neel VA. Strategies to improve facial scars following Mohs micrographic surgery.. 2025. https://doi.org/10.1080/14764172.2025.2496646

This review explicitly states that treatments like topical onion extract lack evidence of efficacy.

The paper trail · every fact has a biography
first checked02 Aug 2026
judged → CONTESTED · 2002 Aug 2026
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