Mechanical ventilation and positive pressure support can be successfully delivered without invasive endotracheal intubation using noninvasive ventilation (NIV), high-flow nasal cannula (HFNC), or continuous positive airway pressure (CPAP) under specific clinical conditions.
The claim states that mechanical ventilation can be performed without invasive intubation under specific conditions. Multiple clinical guidelines and studies (papers 1, 4, 6, 8, 9) confirm that noninvasive respiratory support modalities (such as NIV, HFNC, and CPAP) are routinely and effectively used to provide mechanical support and avoid intubation in patients with specific criteria (e.g., moderate hypoxemia or hypercapnia). Therefore, the claim is supported.