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the claim

LSD induces functional connectivity between disparate sensory regions in the brain

the verdict

SUPPORTED

the evidence backs this

confidence 75/100

Neuroimaging studies demonstrate that LSD alters brain network organization by increasing functional coupling and crosstalk between disparate sensory and association regions.

Evidence for · 2

LSD-induced changes in the functional connectivity of distinct thalamic nuclei.

2023 · cited by 0

LSD intake increased thalamocortical functional connectivity between subcortical nuclei and sensory cortices such as the somatosensory and auditory networks.

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More for · 1

Serotonergic psychedelic drugs LSD and psilocybin reduce the hierarchical differentiation of unimodal and transmodal cortex.

2022 · cited by 0

LSD administration reduced the hierarchical differentiation of the brain, resulting in increased unimodal-transmodal crosstalk.

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first checked01 Aug 2026

judged → SUPPORTED · 7501 Aug 2026

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