Long-term or chronic caffeine use impacts human cognitive function and memory performance, with studies showing both potential neuroprotective benefits and specific memory impairments depending on the context and timing of consumption.
Evidence for · 4
Caffeine in Aging Brains: Cognitive Enhancement, Neurodegeneration, and Emerging Concerns About Addiction.
2025 · cited by 1
Caffeine in aging brains: cognitive enhancement, neurodegeneration, and emerging concerns about addiction (2025) notes that prolonged caffeine use and chronic exposure induce neuroadaptive changes and can lead to cognitive impairment or affect memory in older populations.
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Caffeine attenuates cisplatin induced microglial reactivity and cognitive dysfunction.
2026 · cited by 0
Caffeine attenuates cisplatin induced microglial reactivity and cognitive dysfunction (2026) shows that caffeine confers protection against memory impairments and cognitive deficits in a mouse model.
Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition.
2026 · cited by 0
Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition (2026) demonstrates that habitual coffee intake is associated with differences in memory performance.
Caffeine reduces accuracy in face recognition memory consolidation.
2025 · cited by 0
Caffeine reduces accuracy in face recognition memory consolidation (2025) finds that post-encoding caffeine consumption impacts face recognition memory consolidation, resulting in a general impairment in recognition performance.