Leptin levels correlate directly with total body fat mass
Multiple studies consistently demonstrate that circulating leptin levels have a strong positive correlation with total body fat mass and body mass index.
The retrieved literature consistently supports the claim that leptin levels correlate directly with total body fat mass, showing significant positive correlations across various demographics including adults, adolescents, and children. No papers refute this fundamental physiological relationship.
Muhammad Fg Siregar, Masakazu Terauchi, Rizka A Sari, Cut A Adella, Muhammad O Prabudi, Melvin Ng Barus, Riza Rivany, Immanuel Dl Tobing, Selly Azmeila. Comparison of leptin and estrone levels between normal body mass index and obese menopausal women.. 2024. https://doi.org/10.52225/narra.v4i2.745
This study found a strong positive correlation between body mass index and serum leptin levels in menopausal women.
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M Wauters, I Mertens, R Considine, I De Leeuw, L Van Gaal. Are leptin levels dependent on body fat distribution in obese men and women?. 1998. https://doi.org/10.1007/BF03339999
This research confirms that leptin levels are strongly related to total body fat and percentage body fat.
W F Blum, P Englaro, S Hanitsch, A Juul, N T Hertel, J Müller, N E Skakkebaek, M L Heiman, M Birkett, A M Attanasio, W Kiess, W Rascher. Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone.. 1997. https://doi.org/10.1210/jcem.82.9.4251
This study demonstrates a strong relationship between leptin levels, body mass index, and percentage body fat in children and adolescents.
Syeda Sadia Fatima, Saad Farooq, Maaida Asif Tauni, Omar Irfan, Faiza Alam. Effect of raised body fat on vitamin D, leptin and bone mass.. 2015. https://pubmed.ncbi.nlm.nih.gov/26627514/
This paper reports that serum leptin is significantly raised in individuals with high body fat percentage and positively correlates with body fat.
Rapheeporn Khwanchuea, Chuchard Punsawad. Associations Between Body Composition, Leptin, and Vitamin D Varied by the Body Fat Percentage in Adolescents.. 2022. https://doi.org/10.3389/fendo.2022.876231
This study indicates that serum leptin levels reflect the degree of obesity and increase alongside body fat mass.
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