Ion channels of the same type produce different cellular responses
the verdict
SUPPORTED
the evidence backs this
confidence 87/100
Multiple studies demonstrate that ion channels of the same type can produce different cellular and electrophysiological responses depending on cell type, subcellular localization, and physiological context.
Evidence for · 3
Ion Channels and Electrophysiological Properties of Astrocytes: Implications for Emergent Stimulation Technologies
2021 · cited by 91
This study demonstrates that astrocytes express a variety of different voltage-dependent and voltage-independent channels that produce diverse electrophysiological responses and intracellular signaling cascades.
See more details
More for · 2
Ion channel expression and electrophysiology of singular human (primary and induced pluripotent stem cell derived) cardiomyocytes
2021 · cited by 11
This paper highlights significant heterogeneity in single-cell electrophysiology, action potential morphology, and ion channel expression among human cardiomyocytes.
A Mathematical Model of the Mouse Atrial Myocyte With Inter-Atrial Electrophysiological Heterogeneity
2020 · cited by 10
This study incorporates heterogeneous electrophysiological properties and variations in membrane ion channel currents between different regions of atrial myocytes into a mathematical model.