Inhibitory connections between neurons can be strengthened through plasticity
the verdict
SUPPORTED
the evidence backs this
confidence 78/100
Neuronal inhibitory connections can indeed be strengthened through various forms of plasticity, such as long-term potentiation at inhibitory synapses mediated by receptor modifications and molecular checkpoints.
Evidence for · 3
A physiological role for GABA
<sub>A</sub>
receptor desensitization – induction of long-term potentiation at inhibitory synapses
2020 · cited by 2
Demonstrates an enduring form of long-term potentiation at inhibitory synapses that elevates synaptic current amplitude following GABA_A receptor desensitization.
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More for · 2
Synaptic plasticity of prefrontal long-range inhibition regulates cognitive flexibility.
2026 · cited by 1
Shows that learning rule shifts potentiate long-range GABAergic synapses from prefrontal parvalbumin-expressing neurons.
Neuroligin-2-Dependent Adhesion Defines a Molecular Checkpoint for Inhibitory Synaptic Plasticity.
2026 · cited by 0
Identifies neuroligin-2-dependent adhesion as a critical mediator and molecular checkpoint for inhibitory long-term potentiation.