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the claim
Individuals can be infected repeatedly with the same cold virus
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
2 sources for · 0 against

Individuals can indeed be infected repeatedly with the same cold-causing viruses, as immunity wanes over time and does not permanently prevent reinfection.

Evidence for · 2
The time course of the immune response to experimental coronavirus infection of man
1990 · cited by 682
Callow et al. (1990) demonstrated that individuals can be reinfected with the homologous coronavirus 229E after antibody levels declined over time.
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The analysis

Clinical challenge studies (such as Callow et al. 1990) and phylogenetic durability analyses (such as Bohm et al. 2021) demonstrate that immunity against endemic human coronaviruses decreases, making repeated reinfections with the same virus possible.

More for · 1
The durability of immunity against reinfection by SARS-CoV-2: a comparative evolutionary study
2021 · cited by 159
Bohm et al. (2021) showed through comparative evolutionary analysis that immunity to human coronaviruses wanes, enabling reinfection.
The paper trail · every fact has a biography
first checked31 Jul 2026
judged → SUPPORTED · 9331 Jul 2026
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