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the claim
Inbreeding is highly efficient at increasing homozygosity in populations.
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
6 sources for · 0 against

Inbreeding consistently increases homozygosity within populations, a process frequently measured and tracked via runs of homozygosity (ROH) and autozygosity across diverse species.

Evidence for · 6
Genetic diversity and the application of runs of homozygosity-based methods for inbreeding estimation in German White-headed Mutton sheep
2021 · cited by 17
Paper 0 discusses genomic inbreeding coefficients computed based on runs of homozygosity, highlighting how inbreeding elevates homozygosity.
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The analysis

The retrieved papers consistently support the claim that inbreeding increases homozygosity, frequently discussing it through the lens of runs of homozygosity (ROH), autozygosity, and identity by descent. None of the sources refute the premise. Therefore, the balance verdict is SUPPORTED.

More for · 5
Population Genomic History of the Endangered Anatolian and Cyprian Mouflons in Relation to Worldwide Wild, Feral, and Domestic Sheep Lineages
2023 · cited by 12
Paper 1 notes that runs of homozygosity reflect the genetic impacts of small population sizes and related demographic processes.
Using runs of homozygosity and machine learning to disentangle sources of inbreeding and infer self-fertilization rates
2024 · cited by 1
Paper 5 explains that runs of homozygosity are indicative of elevated homozygosity and inbreeding due to the mating of closely related individuals.
Genomic partitioning and functional dissection of inbreeding depression for stature in Brown Swiss cattle.
2026 · cited by 0
Paper 6 links high genomic inbreeding coefficients directly to extensive runs of homozygosity in livestock populations.
Genotypic and phenotypic consequences of domestication in dogs.
2026 · cited by 0
Paper 7 explores runs of homozygosity as genomic regions arising from shared ancestry and intensive breeding practices.
Evolution of Methods for the Quantitative Assessment of Inbreeding in Livestock.
2026 · cited by 0
Paper 8 defines inbreeding as a quantitative measure of autozygosity that reflects identity by descent and runs of homozygosity.
The paper trail · every fact has a biography
first checked04 Aug 2026
judged → SUPPORTED · 8304 Aug 2026
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