Humans can experience allergic reactions to viral infections
Viral infections can provoke immune alterations, such as increased IgE production and Th2 polarization, that trigger or exacerbate allergic reactions and symptoms.
The retrieved literature documents how viral infections (such as SARS-CoV-2 and rhinoviruses) can drive type-2 inflammation, increase IgE levels, and foster pro-allergic immune responses that lead to allergic exacerbations and conditions. Therefore, the claim is supported by the evidence.
Filippatos F, Matara DI, Michos A, Kakleas K. Immunological Mechanisms Underlying Allergy Predisposition After SARS-CoV-2 Infection in Children.. 2025. https://doi.org/10.3390/cells14191511
This review discusses how viral infections like SARS-CoV-2 promote Th2 polarization and a pro-allergic immune milieu, predisposing individuals to allergic disorders.
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Akhavan M, Yousefi P, Tabibzadeh A. Exacerbations and Management of Asthma in Viral Lower Respiratory Tract Infections: The Significance of Immunoglobulin E.. 2026. https://doi.org/10.1002/iid3.70386
This study highlights how viral respiratory infections trigger heightened serum IgE levels and exacerbate allergic inflammatory pathways and asthma symptoms.
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