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the claim
Human core body temperature evolved as an optimal trade-off against fungal infections
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
3 sources for · 0 against

Evidence supports the hypothesis that mammalian endothermy and high core body temperatures evolved as an optimal trade-off providing a thermal exclusion zone against fungal infections.

Evidence for · 3
2022 · cited by 104
States that elevated temperatures create a thermal restriction zone protecting mammals from most fungal species.
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The analysis

Papers 2, 5, and 10 explicitly discuss how mammalian endothermy and high body temperatures function as a thermal restriction zone protecting against fungal pathogens, with paper 5 specifically modeling this as an evolutionary trade-off between metabolic costs and fungal disease resistance. No papers refute the claim.

More for · 2
2010 · cited by 86
Demonstrates through mathematical modeling that mammalian endothermy optimizes the trade-off between the metabolic costs of maintaining high body temperature and the fitness benefit of a thermal exclusion zone against fungal disease.
2017 · cited by 38
Explains that low mammalian susceptibility to fungal diseases is largely determined by the thermal gradient acting as a protective barrier against environmental fungi.
The paper trail · every fact has a biography
first checked04 Aug 2026
judged → SUPPORTED · 8804 Aug 2026
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