Having weak A or B blood antigens has clinical implications.
the verdict
SUPPORTED
the evidence backs this
confidence 89/100
Having weak A or B blood antigens has significant clinical implications, particularly concerning transfusion compatibility and specific variant phenotypes.
Evidence for · 3
Biological and clinical aspects of ABO blood group system
2008 · cited by 167
Paper [2] highlights that ABO blood group antigens are essential in transfusion medicine for evaluating donor compatibility and hemocyte lifespan.
See more details
More for · 2
Human ABO gene transcriptional regulation
2020 · cited by 47
Paper [7] details how weak phenotypes and alterations in A or B antigens involve specific regulatory variants and pathological conditions such as cancer.
PROCEEDINGS FROM THE INTERNATIONAL SOCIETY OF BLOOD TRANSFUSION WORKING PARTY ON IMMUNOHAEMATOLOGY, WORKSHOP ON THE CLINICAL SIGNIFICANCE OF RED BLOOD CELL ALLOANTIBODIES, SEPTEMBER 9, 2016, DUBAI: Clinical significance of antibodies to antigens in the ABO, MNS, P1PK, Rh, Lutheran, Kell, Lewis, Duffy, Kidd, Diego, Yt, and Xg blood group systems
2019 · cited by 28
Paper [10] confirms that the ABO system is the most clinically important blood group system regarding transfusion safety.