Having cold hands causes physical pain due to vasoconstriction and ischemia
the verdict
SUPPORTED
the evidence backs this
confidence 88/100
Evidence from physiological and epidemiological studies indicates that cold exposure causes peripheral vasoconstriction and ischemia, which leads to increased pain and discomfort in the extremities.
Evidence for · 3
Responses of the hands and feet to cold exposure
2015 · cited by 123
Demonstrates that cold exposure causes strong vasoconstriction in extremities that increases physical pain.
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More for · 2
Cold exposure induces vaso-occlusion and pain in sickle mice that depend on complement activation.
2023 · cited by 15
Shows that cold-induced vasoconstriction leads to ischemia and subsequent vaso-occlusive pain episodes in models of vascular stress.
Occupational cold exposure is associated with upper extremity pain
2023 · cited by 7
Finds that occupational ambient cold exposure and cooling are significantly associated with musculoskeletal pain in the upper extremities.