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the claim
Hair turns grey or white due to the progressive loss of melanocyte stem cells in hair follicles
the verdict
SUPPORTED
the evidence backs this
confidence 92/100

Scientific evidence consistently supports the mechanism that hair turns grey or white due to the progressive loss and defective maintenance of melanocyte stem cells within hair follicles.

Evidence for · 3
Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche
2005 · cited by 627
Demonstrates that hair graying is caused by defective self-maintenance and depletion of melanocyte stem cells within the hair follicle niche.
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More for · 2
Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation
2011 · cited by 263
Explains that melanocyte stem cells serve as the vital reservoir for hair pigmentation and links their depletion to hair greying.
Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying
2025 · cited by 3
Shows that mitochondrial dysfunction leads to the exhaustion of melanocyte stem cells, directly resulting in hair greying.
The paper trail · every fact has a biography
first checked01 Aug 2026
judged → SUPPORTED · 9201 Aug 2026
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