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the claim
Gut motility is controlled by the enteric nervous system and hormonal signals
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
5 sources for · 0 against

Multiple physiological studies confirm that gut motility is regulated by a combination of the enteric nervous system and hormonal signals.

Evidence for · 5
Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation
2023 · cited by 37
Discusses the role of the enteric nervous system and hormonal/neurotransmitter signals in controlling gastrointestinal motility.
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The analysis

The retrieved papers consistently support the claim that gut motility is controlled by both the enteric nervous system and hormonal or neuroendocrine signals, with no papers refuting this well-established physiological principle.

More for · 4
Pentagastrin induced motility pattern in the human upper gastrointestinal tract is reversed by proglumide.
1984 · cited by 8
Demonstrates that hormonal signals such as gastrin alter gut motility patterns.
Involvement of the Gut Chemosensory System in the Regulation of Colonic Anion Secretion
2015 · cited by 6
Shows that gastrointestinal motility is influenced via both hormonal and neuronal pathways.
Purinergic signaling in the gastrointestinal tract
2008 · cited by 4
Reviews how the gastrointestinal tract and its motility are controlled by nerves and hormonal signaling molecules.
Gut motility and its control
2021 · cited by 2
Explains that smooth muscle contractions governing gut motility are influenced by neural and hormonal input.
Everything we examined (12)
  1. Diabetic Microvascular Disease: An Endocrine Society Scientific Statement.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  2. Serotonergic Control of Gastrointestinal Development, Motility, and Inflammationpeer-reviewedsupports
  3. Genome-wide association studies: utility and limitations for research in physiology.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  4. Pentagastrin induced motility pattern in the human upper gastrointestinal tract is reversed by proglumide.peer-reviewedsupports
  5. Understanding the gastrointestinal tract in obesity: From gut motility patterns to enzyme secretionpeer-reviewedno side takennot shown: read and judged not to bear on this claim
  6. Involvement of the Gut Chemosensory System in the Regulation of Colonic Anion Secretionpeer-reviewedsupports
  7. Cell and tissue reprogramming: Unlocking a new era in medical drug discovery.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  8. Purinergic signaling in the gastrointestinal tractpeer-reviewedsupports
  9. Dopamine and the Gut Microbiota: Interactions Within the Microbiota-Gut-Brain Axis and Therapeutic Perspectives.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  10. Gut motility and its controlpeer-reviewedsupports
  11. Mechanisms and clinical implications of gut-brain interactions.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  12. A Roadmap for Advancing Women's Health in Disorders of the Gut-Brain Interaction.peer-reviewedno side takennot shown: read and judged not to bear on this claim
The paper trail · every fact has a biography
first checked05 Aug 2026
judged → SUPPORTED · 8505 Aug 2026
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