Evidence from clinical literature and systematic reviews robustly supports the mechanism that fluoride prevents tooth decay by promoting enamel remineralization and inhibiting demineralization.
The retrieved literature consistently confirms that fluoride prevents dental caries by shifting the demineralization-remineralization balance in favor of remineralization and strengthening dental hard tissues (e.g., forming fluorhydroxyapatite or calcium fluoride precipitates). Multiple reviews, clinical studies, and meta-analyses support this mechanism without conflicting evidence refuting the core claim.