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the claim
Fingers wrinkle in water due to an autonomic nervous system response
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
3 sources for · 0 against

Scientific literature confirms that water-induced finger wrinkling is driven by vasoconstriction regulated by the sympathetic nervous system.

Evidence for · 3
2014 · cited by 14
States explicitly that human skin wrinkling after water exposure is a sympathetic nervous system-dependent process.
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The analysis

Multiple papers, including Wilder et al. (2014) and Lima et al. (2025), explicitly state or investigate water-immersion finger wrinkling as a sympathetic nervous system-dependent process. There are no refuting studies in the provided set.

More for · 2
2022 · cited by 3
Discusses the stimulated skin wrinkling test as a procedure used to quantify sympathetic nerve function.
2025 · cited by 1
Notes that stimulated skin wrinkling reflects the integrity of the autonomic nervous system, eccrine sweat glands, and microcirculation.
Everything we examined (12)
  1. Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR).peer-reviewedno side takennot shown: read and judged not to bear on this claim
  2. Recent Progress in Active Mechanical Metamaterials and Construction Principles.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  3. Mechanisms of tactile sensory deterioration amongst the elderly.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  4. Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  5. Mutual Relationship Between Sleep Disorders, Quality of Life and Psychosocial Aspects in Patients With Psoriasis.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  6. The physical examination as a window into autonomic disorders.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  7. Omics Insights into Animal Resilience and Stress Factors.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  8. Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objectspeer-reviewedsupports
  9. The applicability of the digit wrinkle scan to quantify sympathetic nerve function.peer-reviewedsupports
  10. Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  11. Water-immersion finger-wrinkling improves grip efficiency in handling wet objects.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  12. Influence of Physical, Chemical, and Sympathetic Stimuli on Water-Immersion Finger Wrinklingpeer-reviewedsupports
The paper trail · every fact has a biography
first checked05 Aug 2026
judged → SUPPORTED · 8205 Aug 2026
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