Exogenous mRNA molecules are capable of modifying human DNA
the verdict
SUPPORTED
the evidence backs this
confidence 83/100
Exogenous or viral mRNA molecules can be reverse-transcribed into DNA and integrated into the host genome under specific biological conditions, such as retroviral infection or retrotransposition pathways.
Evidence for · 2
The LTR, v-src, LTR provirus generated in the mammalian genome by src mRNA reverse transcription and integration
1989 · cited by 18
Paper 1 demonstrates that mammalian cells can reverse-transcribe and integrate retroviral mRNA sequences into the genome.
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More for · 1
Epigenetic-Genetic Coupling and Understanding the Molecular and Cellular Basis of Lamarckian Inheritance.
2026 · cited by 1
Paper 8 reviews biological evidence supporting RNA-to-DNA genetic feedback and reverse transcriptase-mediated integration mechanisms.