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the claim
Eukaryotes have a predictable average number of distinct gene products.
the verdict
SUPPORTED
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the weight of evidence
1 source for · 0 against

A peer-reviewed comparative study demonstrates that eukaryotic gene content fits a distinct logarithmic model relative to genome size, indicating predictable patterns in eukaryotic gene numbers.

Evidence for · 1
2009 · cited by 0
The ability to predict gene content is highly desirable for characterization of not-yet sequenced genomes like those of dinoflagellates. Using data from completely sequenced and annotated genomes from phylogenetically diverse lineages, we investigated the relationship between gene content and genome size using regression analyses. Distinct relationships between log10-transformed protein-coding gene number (Y′) versus log10-transformed genome size (X′, genome size in kbp) were found for eukaryotes and non-eukaryotes. Eukaryotes best fit a logarithmic model, Y′ = ln(-46.200+22.678X′, whereas non
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rails:sufficiency:supported:single_source:for=1+0p:against=0+0p | v55:sufficiency

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  1. Distinct Gene Number-Genome Size Relationships for Eukaryotes and Non-Eukaryotes: Gene Content Estimation for Dinoflagellate Genomespeer-reviewedno side taken
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