Multiple studies demonstrate that epithelial cells undergo cell cycle arrest or enter quiescence when subjected to serum deprivation.
The claim is a specific, contestable, and well-supported empirical statement about cellular biology. Multiple retrieved papers explicitly demonstrate that epithelial cells (such as retinal pigment epithelial cells and ovarian cancer cells) undergo cell cycle arrest (such as G0/G1 arrest) when subjected to serum starvation, with none of the provided papers refuting this physiological response.