trustme.bro/r/…
✓ checked
trust me, bro:
here is the receipt.
the claim
Epigenetic marks are faithfully transmitted through both mitosis and meiosis
the verdict
CONTESTED
the evidence cuts both ways
confidence 29/100

While certain specialized epigenetic marks and small RNAs can occasionally bypass reprogramming and be transmitted across generations (transgenerational epigenetic inheritance), the vast majority of epigenetic marks are actively erased and reset during both mitosis and, especially, meiosis.

Evidence for · 3
A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory
2025 · cited by 3
Paper [5] demonstrates that specific SET-domain proteins help maintain transgenerational epigenetic memory in the germline across generations.
Evidence against · 3
Transgenerational inheritance or resetting of stress-induced epigenetic modifications: two sides of the same coin
2015 · cited by 62
Paper [0] argues that transgenerational inheritance is not general and that non-transmission or resetting of epigenetic marks through meiosis is widespread.
See more details
More for · 2
Transgenerational Transmission of Epigenetic Marks During Reproduction in Arabidopsis
2025 · cited by 2
Paper [6] highlights that certain plants achieve transgenerational epigenetic inheritance by transmitting repressive marks like DNA methylation and H3K27me3 through reproduction.
Transgenerational Non-Genomic Transmission of Acquired Nervous System Phenotypes: Narrative Review and Epigenetic Insights.
2025 · cited by 1
Paper [7] notes that specific epigenetic pathways, such as DNA methylation at metastable epialleles, can escape erasure and transmit acquired phenotypes across generations.
More against · 2
Source cell-type epigenetic memory persists in induced pluripotent cells but is lost in subsequently derived germline cells
2024 · cited by 10
Paper [2] shows that extensive epigenetic reprogramming occurs during germline development, erasing source cell memory.
Transgenerational Transmission of Epigenetic Marks During Reproduction in Arabidopsis
2025 · cited by 2
Paper [6] notes that, in general, epigenetically modified parental chromatin is extensively erased by reprogramming during reproduction, leaving little possibility of being inherited.
The paper trail · every fact has a biography
first checked01 Aug 2026
judged → CONTESTED · 2901 Aug 2026
This receipt carries no identity, shared or not. Sharing publishes your connection to it, not your data.
Check your own claim
Challenge the receipt
trust me, bro: win the argument, pass the class, survive peer review.
This receipt is an automated verdict against our published method · not an opinion about any author or publication.
Terms · Privacy · How verdicts work · Dispute this receipt