Enzyme competitive and other standard reversible inhibitions characteristically occur through non-covalent binding interactions.
The retrieved literature consistently links standard reversible enzyme inhibition (including competitive inhibition) to non-covalent binding mechanisms, contrasting it with covalent inhibition which is frequently irreversible. Papers [3] and [11] explicitly support this principle. The rest of the papers discuss various binding modes, kinetics, and natural product inhibitors without refuting the claim.