Environmental elements can act directly as hormones
the verdict
SUPPORTED
the evidence backs this
confidence 77/100
Environmental elements, particularly endocrine-disrupting chemicals found in consumer products and pollutants, can act directly as exogenous hormones or interfere with normal hormone signaling pathways.
Evidence for · 10
Endocrine Disruptors and Other Environmental Influences on Hormone Action
2019 · cited by 1
Reviews how exogenous environmental endocrine-disrupting chemicals interfere with natural hormone synthesis, transport, and receptor binding.
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More for · 9
Endocrine disruptors and endometriosis.
2023 · cited by 0
Details how environmental EDCs such as PCBs and BPA mimic or disrupt estrogen and other hormone pathways to cause disease.
Environmental signaling: from environmental estrogens to endocrine-disrupting chemicals and beyond.
2016 · cited by 0
Explains that environmental contaminants act as xenoestrogens and mimic metabolic signaling molecules.
Genomic evidence based on eQTL data implicates endocrine disruptors as environmental risk factors for estrogen receptor-positive breast cancer.
2025 · cited by 0
Shows that EDC exposure alters gene expression related to hormone receptor-positive cancers.
Environmental endocrine disruptors and amphibian immunity: A bridge between the thyroid hormone axis and T cell development.
2023 · cited by 0
Examines how environmental chemicals and endocrine signals can perturb hormone physiology like the thyroid axis.
Analysis of environmental pollutant Bisphenol F elicited prostate injury targets and underlying mechanisms through network toxicology, molecular docking, and multi-level bioinformatics data integration.
2024 · cited by 0
Highlights how environmental pollutants disrupt endocrine pathways and neuroendocrine regulation.
Mechanisms of disruption of the gut-brain axis by environmental endocrine disruptors.
2025 · cited by 0
Discusses how environmental pollutants disrupt hormone signaling in female reproductive systems.
Endocrine Disruption of the Follicle-Stimulating Hormone Receptor Signaling During the Human Antral Follicle Growth.
2021 · cited by 0
Reviews how chemicals in the environment can inhibit steroidogenesis and disrupt adrenocortical hormones.
Adrenocortical endocrine disruption.
2016 · cited by 0
Demonstrates that freshwater organisms express estrogen receptors that respond directly to xeno-hormones and environmental chemicals.
Freshwater mudsnail (Potamopyrgus antipodarum) estrogen receptor: identification and expression analysis under exposure to (xeno-)hormones.