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the claim
Early NMR spectroscopy linked spectral peaks to specific hydrogen atoms
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
5 sources for · 0 against

Early nuclear magnetic resonance (NMR) spectroscopy successfully linked spectral peaks to specific hydrogen atoms, enabling the structural and chemical analysis of molecules.

Evidence for · 5
Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications.
2017 · cited by 0
Paper 0 discusses how 1H NMR spectroscopy detects unique hydrogen signatures and assigns them to specific metabolites in brain tissue.
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The analysis

The retrieved papers consistently demonstrate that NMR spectroscopy relies on resolving individual spectral peaks (chemical shifts, coupling constants) and assigning them to specific hydrogen atoms (protons) to study molecular and atomic structures.

More for · 4
Solution structure of oxidized rat microsomal cytochrome b5 in the presence of 2 M guanidinium chloride: monitoring the early steps in protein unfolding.
1998 · cited by 0
Paper 1 uses proton NMR spectroscopy to assign specific chemical shifts and monitor local structural changes at individual hydrogen-bearing sites.
Three-dimensional structure of the human immunodeficiency virus type 1 matrix protein.
1994 · cited by 0
Paper 4 details how NMR signal assignments mapped specific hydrogen atoms (such as alpha and backbone amide protons) to determine protein structure.
Binding interactions in early- and late-stage amyloid aggregates of TTR(105-115).
2009 · cited by 0
Paper 5 uses 1H NMR spectroscopy to map atom-specific interactions by linking spectral properties to individual residues and protons.
Two-dimensional NMR spectroscopy: an application to the study of flexibility of protein molecules.
1981 · cited by 0
Paper 8 highlights that individual resonance assignments for specific amino acid protons are a crucial first step for elucidating protein structures using NMR.
The paper trail · every fact has a biography
first checked31 Jul 2026
judged → SUPPORTED · 7531 Jul 2026
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