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the claim
DNA is negatively charged due to its phosphate backbone
the verdict
SUPPORTED
the evidence backs this
confidence 85/100

DNA possesses a net negative charge primarily originating from the phosphate groups present along its backbone structure.

Evidence for · 3
A simple visual method for DNA detection based on the formation of gold nanoparticles
2019 · cited by 34
Paper 0 confirms that double-stranded DNA presents a negative charge due to its exposed phosphate backbone.
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More for · 2
Dodecyltrimethylammonium bromide surfactant effects on DNA: Unraveling the competition between electrostatic and hydrophobic interactions.
2020 · cited by 6
Paper 4 discusses the electrostatic attraction between cationic surfactants and the negative phosphate backbone of DNA.
Differences and Similarities in Protein and Nucleic Acid Structures and Their Biological Interactions.
2025 · cited by 2
Paper 7 notes explicitly that the nucleic acid backbone is negatively charged owing to its phosphate groups.
The paper trail · every fact has a biography
first checked01 Aug 2026
judged → SUPPORTED · 8501 Aug 2026
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