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the claim

Death by lack of sleep is possible in humans

the verdict

SUPPORTED

the evidence backs this

confidence 75/100

Death caused by a lack of sleep is documented in humans through conditions such as fatal familial insomnia and sporadic fatal insomnia, which are uniformly fatal neurodegenerative prion diseases.

Evidence for · 3

Familial and sporadic fatal insomnia.

2003 · cited by 0

Fatal familial insomnia (FFI) and sporadic fatal insomnia present with severe, intractable disruption of sleep leading to fatal neurodegeneration.

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More for · 2

[Fatal familial insomnia].

1999 · cited by 0

Fatal familial insomnia features profound insomnia and thalamic damage, culminating in death.

The prion diseases.

2010 · cited by 0

Fatal insomnia (FI) is recognized as one of the major fatal human prion diseases characterized by severe sleep disruption.

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first checked31 Jul 2026

judged → SUPPORTED · 7531 Jul 2026

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