Cryotherapy and curettage result in different cosmetic outcomes when treating seborrheic keratoses
the verdict
INSUFFICIENT LEANING
refutedsupported
the weight of evidence
3 sources for · 0 against
Available literature acknowledges both cryosurgery and curettage as treatments for seborrheic keratoses and references comparative studies, but the retrieved texts lack detailed findings on their specific cosmetic outcomes.
Seborrheic keratoses.
Seborrheic keratoses are benign tumors of the epidermis that commonly appear during middle age. They are pigmented verrucous papules with a characteristic "stuck on" appearance. The tumors enlarge and become more deeply pigmented with age. The precise etiology is unknown. Differential diagnosis includes malignant melanoma and pigmented basal cell carcinoma. Biopsy should be performed if the diagnosis is in doubt. Treatment, when indicated, includes curettage, shave excision, freezing with liquid nitrogen or the use of trichloroacetic acid.
Published in American family physician (1986)
J. Effectiveness of cryosurgery vs. curettage in the treatment of seborrheic keratoses. JAMA Dermatol. 2013;149(1):108–109. doi: 10.1001/2013.jamadermatol.275. [ DOI ] [ PubMed ] [ Google Scholar ]
10. Gurel MS, Aral BB. Effectiveness of erbium: YAG laser and cryosurgery in seborrheic keratoses: randomized, prospective intraindividual comparison study. J Dermatolog Treat. 2015;26(5):477–480. doi: 10.3109/09546634.2015.1024597. [ DOI ] [ PubMed ] [ Google Scholar ]
11. Draelos ZD, Kempers S, Smith SR et al. Safety and efficacy of A-101 hydrogen peroxide topical solution in adults with seborrheic keratosis: results from the phase 3, randomized double-blind, vehicle-controlled, parallel-group study. Skin J Cutan Med. 2017;1:s119. [ Google Scholar ]
12. Kao SK, Kiss A, Efimova T, Freidman A. Ex vivo evaluation of cytotoxicity and melanocyte viability after A-101 hydrogen peroxide topical solution 40% or cryosurgery treatment in seborrheic keratosis lesions. J Am Acad Dermatol. 2018;79(4):767–768. doi: 10.1016/j.jaad.2018.03.034. [ DOI ] [ PubMed ] [ Google Scholar ]
13. Dubois JC, Jarratt M, Beger BB et al. A-101, a Proprietary topical formulation of high concentration hydrogen peroxide solution: a randomized, double-blind, vehicle controlled, parallel group study of the dose- response profile in subjects with seborrheic keratosis of the face. Dermatol Surg. 2018;44(3):330–340. doi: 10.1097/DSS.0000000000001302. [ DOI ] [ PubMed ] [ Google Scholar ]
14. Lacarrubba F, Nasca MR, Verzi AE, Micali G. A novel topical agent in the treatment of seborrheic keratoses: A concept study by clinical and dermoscopic evaluation. Dermatol Ther. 2017;30(5) doi: 10.1111/dth.12526. [ DOI ] [ PubMed ] [ Google Scholar ]
15. Wood LD, Stucki JK, Hollenbeak CS, Miller JJ. Effectiveness of cryosurgery vs curettage in the treatment of seborrheic keratoses. JAMA Dermatol. 2013;149(1):108–109. doi: 10.1001/2013.jamadermatol.275. [ DOI ] [ PubMed ] [ Google Scholar ]
16. Kenward MG, Roger JH. Smal
Effectiveness of Cryosurgery vs Curettage in the Treatment of Seborrheic Keratoses | Dermatology | JAMA Dermatology | JAMA Network
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Everything we examined (3)
This check searched the claim as stated. It did not run a separate search for evidence against it.