COSY and TOCSY NMR techniques differ in their detection of small couplings between protons.
the verdict
SUPPORTED
the evidence backs this
confidence 90/100
COSY and TOCSY NMR techniques are standard two-dimensional homonuclear correlation experiments that differ in how magnetization is transferred through scalar coupling networks, allowing them to probe different ranges of proton-proton couplings.
Evidence for · 3
In Vivo
NMR Spectroscopy
2019 · cited by 247
Reviews basic principles of two-dimensional NMR including COSY and spin-echo or J-resolved methods used to evaluate scalar coupling and J-coupling differences.
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More for · 2
Complete <sup>1</sup>H and <sup>13</sup>C assignment of Lys and Leu sidechains of staphylococcal nuclease using HCCH‐COSY and HCCH‐TOCSY 3D NMR spectroscopy
1991 · cited by 8
Compares HCCH-COSY and HCCH-TOCSY 3D NMR techniques for their distinct correlation capabilities in sidechain assignments.
Bimolecular Sandwich Aggregates of Porphyrin Nanorings.
2024 · cited by 4
Utilizes both 1H-1H COSY and TOCSY alongside other methods as part of a suite where different coupling pathways are detected.