Core body temperature significantly affects human lifespan
Core body temperature significantly affects human and animal lifespan, with evidence indicating that lower body temperatures promote longevity and healthspan.
The claim is specific, empirical, and directly supported by recent scientific reviews and experimental studies showing a clear link between core body temperature regulation and lifespan.
Bruno Conti, R. de Cabo. Promoting health and survival through lowered body temperature. 2025. https://doi.org/10.1038/s43587-025-00850-0
Conti and de Cabo (2025) summarize evidence demonstrating that core body temperature is a long-established determinant of longevity across species and that reducing it increases lifespan.
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Mori K, Imai SI. Muscle-derived Mimecan regulates hypothalamus-brown adipose tissue communication and promotes health and lifespan in mice.. 2026. https://doi.org/10.1016/j.cmet.2026.04.003
The study by skeletal muscle research shows that regulating core body temperature via brown adipose tissue impacts systemic health and significantly extends lifespan in mammals.
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