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the claim
Consuming food contaminated by rodent saliva or pests poses a significant risk of zoonotic pathogen transmission.
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SUPPORTED
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2 sources for · 0 against

Peer-reviewed literature establishes that rodents can transmit pathogens indirectly when they contaminate raw foods or water supplies with zoonotic pathogens via saliva, feces, or urine, which are subsequently ingested by humans.

Evidence for · 2
2021 · cited by 10
<i>Cryptosporidium</i> spp. are protozoan parasites that infect perhaps all vertebrate animals, with a subset of species and genotypes that function as food- and waterborne pathogens. The objective of this work was to collate the <i>Cryptosporidium</i> species and genotypes from common wild rodents on the west coast of the USA and update the information regarding the zoonotic potential of <i>Cryptosporidium</i> from these ubiquitous wild species. Representative sequences of the 18S rRNA gene for a unique set of <i>Cryptosporidium</i> isolates obtained from deer mice, house mice, mountain beavers, yellow-bellied marmot, long-tailed vole, California ground squirrels, Belding's ground squirrels, and a golden-mantled ground squirrel in GenBank were selected for phylogenetic analysis. Phylogenetic and BLAST analysis indicated that 4 (18%) of the 22 unique <i>Cryptosporidium</i> sequences from these wild rodent species were 99.75% to 100% identical to known zoonotic species (<i>C. parvum</i>, <i>C. ubiquitum</i>, <i>C. xiaoi</i>), suggesting that a minority of these representative <i>Cryptosporidium</i> isolates could have a public health impact through food and waterborne routes of human exposure. These zoonotic isolates were shed by deer mice and a yellow-bellied marmot from California, and from a mountain beaver trapped in Oregon. In addition, the group of unique <i>Cryptosporidium</i> isolates from deer mice and ground dwelling squirrels exhibited considerable DNA diversity, with multiple isolates appearing to be either host-limited or distributed throughout the various clades within the phylogenetic tree representing the various <i>Cryptosporidium</i> species from host mammals. These results indicate that only a subset of the unique <i>Cryptosporidium</i> genotypes and species obtained from wild rodents on the US west coast are of public health concern; nevertheless, given the geographic ubiquity of many of these host species and often high density at critical locati Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( https://creativecommons.org/licenses/by/4.0/ ). Abstract Cryptosporidium spp. are protozoan parasites that infect perhaps all vertebrate animals, with a subset of species and genotypes that function as food- and waterborne pathogens. The objective of this work was to collate the Cryptosporidium species and genotypes from common wild rodents on the west coast of the USA and update the information regarding the zoonotic potential of Cryptosporidium from these ubiquitous wild species. These results indicate that only a subset of the unique Cryptosporidium genotypes and species obtained from wild rodents on the US west coast are of public health concern; nevertheless, given the geographic ubiquity of many of these host species and often high density at critical locations like municipal watersheds or produce production fields, prudent pest control practices are warranted to minimize the risks of water- and foodborne transmission to humans. Rodents can transmit pathogens to humans in a variety of mechanisms: manual handling or direct contact with rodents; physical contact with rodent feces, urine, or saliva; through rodent bites [ 16 , 18 ]; or indirectly when rodents contaminate raw foods or drinking water supplies with zoonotic pathogens that are subsequently ingested by humans [ 15 , 19 , 20 ]. For example, rodents are reservoirs or can transmit salmonellosis, plague, leptospirosis, and rat-bite fever [ 21 ]. The aim of this work was to consolidate the diversity of Cryptosporidium spp. Although this decision process is not perfect, it is a current convention used by many US state and federal regulatory agencies to assign zoonotic disease risk to an isolate of Cryptosporidium found either in water or on food. 3. Results 3.1. Diverse Genotypes of Relatively Recent Cryptosporidium Isolates from Wild Rodents throughout the West Coast, US Phylogenetic relationships among the 22 unique (non-redundant) 18S rRNA gene sequences from 36 isolates of Cryptosporidium from wild rodents trapped from the US west coast are shown in Figure 1 . Water Quality and Produce Safety Implications from Zoonotic Cryptosporidium in Rodents Cryptosporidium is a common pathogen that ubiquitum, or other zoonotic species or genotypes of Cryptosporidium , along with the observation that rodents like deer mice can shed very high concentrations (>10 8 ) of oocysts per g feces [ 24 ], reasonable control measures may be needed to prevent high population densities of rodents occurring in close proximity to recreational water sources or municipal drinking water supplies that can pose a risk for waterborne transmission to humans and other animals. Despite the relatively small body mass of individual rodents compared to livestock and other larger mammalian wildlife species, the risks of food- and waterborne transmission of zoonotic Cryptosporidium are elevated by the large number of diverse species in the order Rodentia, their ubiquitous geographical distribution from high elevation-montane to lowland-coastal valleys, their ability to form dense populations and focal colonies on municipal watersheds and produce farms when conditions favor reproduction, and the documented occurrence of zoonotic species and genotypes Cryptosporidium in these host species as updated in this current work. 5. Conclusions The current work focused on the genomic diversity of Cryptosporidium in wild rodents from the west coast of the US and to quantify the proportion of unique isolates exhibiting zoonotic infection risk from contaminated produce and water. Based on the group of available sequences of Cryptosporidium in the GenBank from wild rodents from throughout the west coast of the US, a minority of these Cryptosporidium isolates were highly related to known zoonotic species or genotypes of Cryptosporidium .
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A zoonosis (/zoʊˈɒnəsɪs, ˌzoʊəˈnoʊsɪs/ ; pl.: zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent A zoonosis ( ; pl.: zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a virus, bacterium, parasite, fungus or prion) which is transmitted from a non-human animal to a human. When humans infect non-humans, it is called reverse zoonosis or anthroponosis. Major modern diseases such as Ebola and salmonellosis are zoonoses. HIV was a zoo Pets… Hunting involves humans tracking, chasing, and capturing wild animals, primarily for food or materials like fur. However, other reasons like pest control or managing wildlife populations can also exist. Transmission of zoonotic diseases, those leaping from animals to humans, can occur through various routes: direct physical contact, airborne droplets or particles, bites or vector transport by insects, oral ingestion, or even contact with contaminated environments. Wildlife activities like hunting and trade bring humans closer to dangerous zoonotic pathogens, threatening global health. According to the Center for Diseases Control and Prevention (CDC) hunting and consuming wild animal meat ("bushmeat") in regions like Africa can expose people to infectious diseases due to the types of animals involved, like bats and primates. Unfortunately, common preservation methods like smoking or drying aren't enough to eliminate these risks. Although bushmeat provides protein and income for many, the practice is intricately linked to numerous emerging infectious diseases like Ebola, HIV, and SARS, raising critical public health concerns. A review published in 2022 found evidence that zoonotic spillover linked to wildmeat consumption has been reported across all continents. Glanders primarily affects those who work closely with horses and donkeys. Close contact with cattle can lead to cutaneous anthrax infection, whereas inhalation anthrax infection is more common for workers in slaughterhouses, tanneries, and wool mills. Close contact with sheep who have recently given birth can lead to infection with the bacterium Chlamydia psittaci, causing chlamydiosis (and enzootic abortion in pregnant women), as well as increase the risk of Q fever, toxoplasmosis, and listeriosis, in the pregnant or otherwise immunocompromised. Echinococcosis is caused by a tapeworm, which can spread from infected sheep by food or water contaminated by feces or wool. Avian influenza is common in chickens, and, while it is rare in humans, the main public health worry is that a strain of avian influenza will recombine with Pets can transmit a number of diseases. Dogs and cats are routinely vaccinated against rabies. Pets can also transmit ringworm and Giardia, which are endemic in both animal and human populations. Toxoplasmosis is a common infection of cats; in humans it is a mild disease although it can be dangerous to pregnant women. Dirofilariasis is caused by Dirofilaria immitis through mosquitoes infected by mammals like dogs and cats. Cat-scratch disease is caused by Bartonella henselae and Bartonella quintana, which are transmitted by fleas that are endemic to cats. Toxocariasis is the infection of humans by any of species of roundworm, including species specific to dogs (Toxocara canis) or cats (Toxocara cati). Cryptosporidiosis can be spread to humans from pet lizards, such as the leopard gecko. Encephalitozoon cuniculi is a microsporidial parasite carried by many mammals, including rabbits, and is an important opportunistic pathogen in people immunocompromised by HIV/AIDS, organ transplantation, or CD4+ T-lymphocyte deficiency. Pets may also serve as a reservoir of viral disease and contribute to the chronic presence of certain viral diseases in the human population. For instance, approximately 20% of domestic dogs, cats, and horses carry anti-hepatitis E virus antibodies and thus these animals probably contribute to human hepatitis E burden as well. For non-vulnerable populations (e.g., people who are not immunocompromised) the associated disease burden is, however, small. Furthermore, the trade of non-domestic animals such as wild animals as pets can also increase the risk of zoonosis spread. Bats are frequently unjustly portrayed as the primary instigators of the ongoing COVID-19 epidemic; nevertheless, the true origins of this and other zoonotic spillover occurrences should be attributed to human environmental impacts, especially the proliferation of pets. For example, bat predation by cats poses a significant danger to biodiversity conservation and carries zoonotic consequences that must be acknowledged. Hunting involves humans tracking, chasing, and capturing wild animals, primarily for food or materials like fur. However, other reasons like pest control or managing wildlife populations can also exist. Transmission of zoonotic diseases, those leaping from animals to humans, can occur through various routes: direct physical contact, airborne droplets or particles, bites or vector transport by insects, oral ingestion, or even contact with contaminated environments. Wildlife activities like hunting and trade bring humans closer to dangerous zoonotic pathogens, threatening global health. According to the Center for Diseases Control and Prevention (CDC) hunting and consuming wild animal meat ("bushmeat") in regions like Africa can expose people to infectious diseases due to the types of animals involved, like bats and primates. Unfortunately, common preservation methods like smoking or drying aren't enough to eliminate these risks. Although bushmeat provides protein and income for many, the practice is intricately linked to numerous emerging infectious diseases like Ebola, HIV, and SARS, raising critical public health concerns. A review published in 2022 found evidence that zoonotic spillover linked to wildmeat consumption has been reported across all continents.
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  1. Zoonosisreferenceno side taken
  2. Diverse Genotypes and Species of <i>Cryptosporidium</i> in Wild Rodent Species from the West Coast of the USA and Implications for Raw Produce Safety and Microbial Water Quality.peer-reviewedno side taken
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first checked06 Aug 2026
judged → SUPPORTED · 8206 Aug 2026
held for human review08 Aug 2026
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